Analogs generation software

  • Library synthesizer Virtual chemical enumeration
  • SmiLib It is a freely available Linux based chemoinformatics tool which can be used as command line and graphical user interface for generating combinatorial library.
  • GLARE GLARE (Global Library Assessment of Reagents) is an Open Source package to generate the combinatorial library.
  • CLEVER CLEVER (chemical library editing, visualizing and enumerating resource) is a free chemoinformatics tool that enumerates chemical libraries using customized fragments; it also computes the physicochemical properties of the generated compounds
  • Newlead based tool for chemical library enumeration and profiling. NEWLEAD is also used for the automatic generation of combinatorial library from bioactive conformations of reference molecules.