Main Objectives of the Project
- Structural and computational characterization of ligand reorganization mechanism of PKD/ VEGFR-2
- Identification of potent PKD/ VEGFR-2 tyrosine kinase inhibitors through structure-ligand guided virtual screening and molecular dynamics simulation approach.
- Selection of hits for biological testing -Virtually screened hits will be then evaluated for their inhibitory activities against PKD /VEGFR-2 tyrosine kinase, Identification and characterization of enzyme inhibitors, Quantification of binding thermodynamics etc
Research Students: Under S. M. Zahid Hosen Supervision:
- Raju Dash- MS (Thesis)Biotechnology and molecular biology department, Faculty Basic Biomedical and Pharmaceutical Science, University of Science and Technology Chittagong.